Bergknut, Niklas
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
Research article2013Peer reviewed
Intervertebral disc degeneration in the dog. Part 2: Chondrodystrophic and non-chondrodystrophic breeds
Smolders, Lucas A.; Bergknut, Niklas; Grinwis, Guy C.M.; Hagman, Ragnvi; Lagerstedt, Anne-Sofie; Hazewinkel, Herman; Tryfonidou, Marianna A.; Meij, Björn P.
Abstract
Dogs can be grouped into two distinct types of breed based on the predisposition to chondrodystrophy, namely, non-chondrodystrophic (NCD) and chondrodystrophic (CD). In addition to a different process of endochondral ossification, NCD and CD breeds have different characteristics of intravertebral disc (IVD) degeneration and IVD degenerative diseases. The anatomy, physiology, histopathology, and biochemical and biomechanical characteristics of the healthy and degenerated IVD are discussed in the first part of this two-part review. This second part describes the similarities and differences in the histopathological and biochemical characteristics of IVD degeneration in CD and NCD canine breeds and discusses relevant aetiological factors of IVD degeneration. (C) 2012 Elsevier Ltd. All rights reserved.
Keywords
Intervertebral disc; Degeneration; Hernia; Dog; Chondrodystrophic; Non-chondrodystrophic; Notochordal cell
Published in
Veterinary Journal
2013, Volume: 195, number: 3, pages: 292-299
Publisher: ELSEVIER SCI LTD
Hagman, Ragnvi
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
Lagerstedt, Anne-Sofie
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
SLU Authors
UKÄ Subject classification
Neurology
Clinical Science
Orthopedics
Publication identifier
DOI: https://doi.org/10.1016/j.tvjl.2012.10.011
Permanent link to this page (URI)
https://res.slu.se/id/publ/43825