Spider silk fusion protein structures incorporating immunoglobulin fragments as affinity ligands

Abstract

A recombinant fusion protein comprising the moieties Band CT, and optionally REP, wherein B is comprising at least one immunoglobulin fragment, which provides the capacity of selective interaction with an organic target; CT is a moiety of from 70 to 120 amino acid residues and is derived from the C-terminal fragment of a spider silk protein; and REP is a moiety of from 70 to 300 amino acid residues and is derived from the repetitive fragment of a spider silk protein.

Published in

Application number: US14/398,361
Patent number: US9856308B2
Application published date: 2015-04-30
Publication date: 2018-01-02

SLU Authors

• Hedhammar, My

  • Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences
    

• Johansson, Jan

  • Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences
    

• Rising, Anna

  • Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Biomedical Laboratory Science/Technology


More information

Assignee: SPIBER TECHNOLOGIES AB . Stockholm (SE)


Permanent link to this page (URI)

https://res.slu.se/id/publ/44357