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Patent2018

Spider silk fusion protein structures incorporating immunoglobulin fragments as affinity ligands

Hedhammar, My; Johansson, Jan; Rising, Anna; Nygren, Per-Åke

Abstract

A recombinant fusion protein comprising the moieties Band CT, and optionally REP, wherein B is comprising at least one immunoglobulin fragment, which provides the capacity of selective interaction with an organic target; CT is a moiety of from 70 to 120 amino acid residues and is derived from the C-terminal fragment of a spider silk protein; and REP is a moiety of from 70 to 300 amino acid residues and is derived from the repetitive fragment of a spider silk protein.

Published in


Application number: US14/398,361
Patent number: US9856308B2
Application published date: 2015-04-30
Publication date: 2018-01-02