Skip to main content
SLU publication database (SLUpub)

Patent2013

Monomeric N-terminal spider silk protein domain and uses thereof

Johansson, Jan; Nordling, Kerstin; Rising, Anna

Abstract

A novel protein is comprising a moiety of 100-160 amino acid residues having at least 80% identity with the N-terminal moiety of a spider silk protein, wherein the amino acid residue corresponding to position 72 in SEQ ID NO 1 is not Ala or Gly. The protein moiety is useful in a fusion protein for enhancing the solubility of another moiety in the fusion protein, which is a desired protein or polypeptide. Novel methods are provided for producing such a fusion protein, and optionally a desired protein or polypeptide from said fusion protein.

Published in


Application number: 12162642.8
Patent number: EP2644619A1
Application published date: 2013-10-02
Publication date: 2013-10-02