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Research article2009Peer reviewedOpen access

Genome scan detects quantitative trait loci affecting female fertility traits in Danish and Swedish Holstein cattle

Höglund, Johanna Karolina; Guldbrandtsen, B.; Su, G; Thomsen, B.; Lund, M.S.

Abstract

Data from the joint Nordic breeding value prediction for Danish and Swedish Holstein grandsire families were used to locate quantitative trait loci (QTL) for female fertility traits in Danish and Swedish Holstein cattle. Up to 36 Holstein grandsires with over 2,000 sons were genotyped for 416 microsatellite markers. Single trait breeding values were used for 12 traits relating to female fertility and female reproductive disorders. Data were analyzed by least squares regression analysis within and across families. Twenty-six QTL were detected on 17 different chromosomes. The best evidence was found for QTL segregating on Bos taurus chromosome (BTA) 1, BTA7, BTA10, and BTA26. On each of these chromosomes, several QTL were detected affecting more than one of the fertility traits investigated in this study. Evidence for segregation of additional QTL on BTA2, BTA9, and BTA24 was found.

Keywords

quantitative trait locus; genome-wide scan; female fertility

Published in

Journal of Dairy Science
2009, Volume: 92, number: 5, pages: 2136-2143 Publisher: AMER DAIRY SCIENCE ASSOC-ADSA

    UKÄ Subject classification

    Genetics

    Publication identifier

    DOI: https://doi.org/10.3168/jds.2008-1104

    Permanent link to this page (URI)

    https://res.slu.se/id/publ/44596