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Research article - Peer-reviewed, 2012

Efficient recovery of whole blood RNA - a comparison of commercial RNA extraction protocols for high-throughput applications in wildlife species

Schwochow, Doreen; Serieys, Laurel E.K.; Wayne, Robert K.; Thalmann, Olaf


Conclusion: By carefully choosing the appropriate RNA extraction method, whole blood can become a valuable source for high-throughput applications like expression arrays or transcriptome sequencing from natural populations. Additionally, candidate genes showing signs of selection could subsequently be genotyped in large population samples using whole blood as a source for RNA without harming individuals from rare or endangered species.


Whole blood; RNA preservation; RNA extraction; DNA contamination; Transcriptome sequencing; Globin transcripts

Published in

BMC Biotechnology
2012, volume: 12, pages: 1-11

Authors' information

Schwochow, Doreen
Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics
Serieys, Laurel E.K.
University of California Los Angeles (UCLA)
Wayne, Robert K.
Thalmann, Olaf
University of California Los Angeles (UCLA)

UKÄ Subject classification

Other Environmental Biotechnology

Publication Identifiers


URI (permanent link to this page)