CYP 3A in horse

Abstract

The intestinal enterocytes provide the initial site for cytochrome P450 (CYP)-mediated metabolism of orally absorbed xenobiotics. In man and some animal species, the CYP 3A subfamily is highly expressed in the intestines and considered to be important in the first-pass metabolism of drugs and other xenobiotics. Aim: to investigate the mRNA expression, immunohistochemical localization and catalytic activity of CYP 3A in the intestines of horse

Keywords

CYP 3A; horse

Published in

Toxicology and Applied Pharmacology
2004, volume: 201, pages: 112-119

SLU Authors

• Tyden, Eva

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Olsén, Lena

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Larsson, Pia

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Tjälve, Hans

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Tallkvist, Jonas

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Clinical Science

Permanent link to this page (URI)

https://res.slu.se/id/publ/4570