Complete genome sequence of Brachyspira intermedia reveals unique genomic features in Brachyspira species and phage-mediated horizontal gene transfer

Håfström, Therese; Jansson, Monica Desiree Seger; Segerman, Bo

doi:10.1186/1471-2164-12-395

Research article - Peer-reviewed, 2011

Complete genome sequence of Brachyspira intermedia reveals unique genomic features in Brachyspira species and phage-mediated horizontal gene transfer

Håfström, Therese; Jansson, Monica Desiree Seger; Segerman, Bo

Abstract

Conclusions: The accessory gene pool shapes species-specific traits. It is also influenced by reductive genome evolution and horizontal gene transfer. Gene-transfer events can cross both species and genus boundaries and bacteriophages appear to play an important role in this process. A mechanism for horizontal gene transfer appears to be gene translocations leading to remodeling of bacteriophages in combination with broad tropism.

Keywords

Brachyspira intermedia; genome comparison; bacteriophages; horizontal gene transfer; AT/GC-skew

Published in

BMC Genomics
2011, volume: 12, article number: 395
Publisher: BIOMED CENTRAL LTD

Authors' information

Håfström, Therese

Jansson, Monica Desiree Seger (Jansson, Desirée)

Swedish University of Agricultural Sciences, Department of Biomedical Science and Veterinary Public Health

Segerman, Bo

UKÄ Subject classification

Genetics
Microbiology

Publication Identifiers

DOI: https://doi.org/10.1186/1471-2164-12-395

URI (permanent link to this page)

https://res.slu.se/id/publ/46484