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Research article2011Peer reviewedOpen access

Complete genome sequence of Brachyspira intermedia reveals unique genomic features in Brachyspira species and phage-mediated horizontal gene transfer

Håfström, Therese; Jansson, Monica Desiree Seger; Segerman, Bo

Abstract

Conclusions: The accessory gene pool shapes species-specific traits. It is also influenced by reductive genome evolution and horizontal gene transfer. Gene-transfer events can cross both species and genus boundaries and bacteriophages appear to play an important role in this process. A mechanism for horizontal gene transfer appears to be gene translocations leading to remodeling of bacteriophages in combination with broad tropism.

Keywords

Brachyspira intermedia; genome comparison; bacteriophages; horizontal gene transfer; AT/GC-skew

Published in

BMC Genomics
2011, Volume: 12, article number: 395
Publisher: BIOMED CENTRAL LTD

    UKÄ Subject classification

    Genetics
    Microbiology

    Publication identifier

    DOI: https://doi.org/10.1186/1471-2164-12-395

    Permanent link to this page (URI)

    https://res.slu.se/id/publ/46484