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Research article - Peer-reviewed, 2011

Effect of frusemide on transvascular fluid fluxes across the lung in exercising horses

Vengust, Modest; Kerr, C.; Stämpfli, Henry R; Pringle, John; Heigenhauser, G. J.; Viel, L.


Fru does not have a measurable effect on J(ER) and J(V-A). Cardiac output was reduced in FruTr, suggesting that there were also smaller changes in the capillary recruitment and transvascular transmural hydrostatic pressures; however, this did not effect J(V-A). Therefore, Fru at the dose of 250 mg does not appear to be an effective treatment for regulating pulmonary transvascular forces during exercise in horses.


horse; exercise-induced pulmonary haemorrhage; pulmonary circulation; water transport; furosemide

Published in

Equine Veterinary Journal
2011, Volume: 43, number: 4, pages: 451-459

      UKÄ Subject classification

      Clinical Science

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