Effect of frusemide on transvascular fluid fluxes across the lung in exercising horses

Vengust, Modest; Kerr, C.; Stämpfli, Henry R; Pringle, John; Heigenhauser, G. J.; Viel, L.

doi:10.1111/j.2042-3306.2010.00301.x

Research article - Peer-reviewed, 2011

Effect of frusemide on transvascular fluid fluxes across the lung in exercising horses

Vengust, Modest; Kerr, C.; Stämpfli, Henry R; Pringle, John; Heigenhauser, G. J.; Viel, L.

Abstract

Fru does not have a measurable effect on J(ER) and J(V-A). Cardiac output was reduced in FruTr, suggesting that there were also smaller changes in the capillary recruitment and transvascular transmural hydrostatic pressures; however, this did not effect J(V-A). Therefore, Fru at the dose of 250 mg does not appear to be an effective treatment for regulating pulmonary transvascular forces during exercise in horses.

Keywords

horse; exercise-induced pulmonary haemorrhage; pulmonary circulation; water transport; furosemide

Published in

Equine Veterinary Journal
2011, volume: 43, number: 4, pages: 451-459
Publisher: WILEY-BLACKWELL

Authors' information

Vengust, Modest

University of Ljubljana

Kerr, C.

University of Guelph

Stämpfli, Henry R

Pringle, John

Swedish University of Agricultural Sciences, Department of Clinical Sciences

Heigenhauser, G. J.

Viel, L.

University of Guelph

UKÄ Subject classification

Clinical Science

Publication Identifiers

DOI: https://doi.org/10.1111/j.2042-3306.2010.00301.x

URI (permanent link to this page)

https://res.slu.se/id/publ/46575