Eriksson, Erik
- Department of Animal Biosciences, Swedish University of Agricultural Sciences
Research article2011Peer reviewedOpen access
Söderlund, R.; Aspán, Anna; La Ragione, R.M.; Eriksson, Erik; Boqvist, Sofia
Verotoxigenic Escherichia coli (VTEC) serotype O157:H7 strains from a Swedish cattle prevalence study (n=32), and livestock-derived strains linked to human disease (n=13), were characterized by microarray and PCR detection of virulence genes. The overall aim of the study was to investigate the distribution of known virulence determinants and determine which genes are linked to increased pathogenicity in humans. A core set of 18 genes or gene variants were found in all strains, while seven genes were variably present. This suggests that the majority of VTEC O157:H7 found in Swedish cattle carry a broad repertoire of virulence genes and should be considered potentially harmful to humans. A single virulence gene type was significantly associated with strains linked to human disease cases (P=0.012), but no genetic trait to explain the increased virulence of this genotype could be found.
Molecular biology; molecular epidemiology; Shiga-like toxin-producing E. coli; zoonotic foodborne diseases
Epidemiology and Infection
2011, Volume: 139, number: 7, pages: 1088-1096 Publisher: CAMBRIDGE UNIV PRESS
Veterinary Science
Animal and Dairy Science
DOI: https://doi.org/10.1017/S095026881000213X
https://res.slu.se/id/publ/46583