Eloranta, Maija-Leena
- Uppsala University
Research article - Peer-reviewed, 2010
Genetic Variants and Disease-Associated Factors Contribute to Enhanced Interferon Regulatory Factor 5 Expression in Blood Cells of Patients With Systemic Lupus Erythematosus
Feng, D; Stone, Rivka C.; Eloranta, Maija-Leena; Sangster-Guity, N; Nordmark, Gunnel; Sigurdsson, Snaevar; Wang, Chuan; Alm, Gunnar; Syvänen, Ann-Christine; Rönnblom, Lars; Barnes, Betsy J.
Abstract
Conclusion. This study provides the first formal proof that IRF-5 expression and alternative splicing are significantly up- regulated in primary blood cells of patients with SLE. Furthermore, the risk haplotype is associated with enhanced IRF-5 transcript and protein expression in patients with SLE.
Published in
Arthritis and Rheumatism
2010, Volume: 62, number: 2, pages: 562-573
Publisher: WILEY-BLACKWELL
Alm, Gunnar
- Department of Biomedical Science and Veterinary Public Health, Swedish University of Agricultural Sciences
- Department of Biomedical Science and Veterinary Public Health, Swedish University of Agricultural Sciences
SLU Authors
UKÄ Subject classification
Rheumatology and Autoimmunity
Publication Identifiers
DOI: https://doi.org/10.1002/art.27223
Permanent link to this page (URI)
https://res.slu.se/id/publ/48073