Sandström, Corine
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
Research article2009Peer reviewed
Kaszowska, Marta; Norgren, Anna S; Arvidson, Per I; Sandström, Corine
Saturation transfer difference (STD) NMR spectroscopy was used to study the interaction of the lectin Vicia villosa (VVLB4) with alpha-D-GalNAc glycosylated beta(3)-peptides. The data were compared to those obtained with the monosaccharides D-Gal, D-GalNAc, and D-Glc as well as with those obtained with the Tn antigen alpha-glycopeptide (D-GalNAc-alpha-O-Ser/Thr), molecule naturally recognized by V. villosa. Evidence that the lectin also recognizes glycosylated beta(3)-peptides and has close contact with both the sugar and amino acid moieties was obtained. (C) 2009 Elsevier Ltd. All rights reserved.
STD NMR; Glycosylated beta(3)-peptides; Tn antigen; Lectin Vicia villosa (isolectin B-4)
Carbohydrate Research
2009, Volume: 344, number: 18, pages: 2577-2580
Publisher: ELSEVIER SCI LTD
Biochemistry and Molecular Biology
Organic Chemistry
DOI: https://doi.org/10.1016/j.carres.2009.06.040
https://res.slu.se/id/publ/48887