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Research article2009Peer reviewed

Ozone oxidation of pharmaceuticals, endocrine disruptors and pesticides during drinking water treatment

Broseus, R.; Vincent, S.; Aboulfadl, K.; Daneshvar, A.; Sauve, S.; Barbeau, B.; Prevost, M.


This study investigates the oxidation of pharmaceuticals, endocrine disrupting compounds and pesticides during ozonation applied in drinking water treatment. In the first step, second-order rate constants for the reactions of selected compounds with molecular ozone (k(O3)) were determined in bench-scale experiments at pH 8.10: caffeine (650 +/- 22 M(-1) s(-1)), progesterone (601 +/- 9 M(-1)s(-1)), medroxyprogesterone (558 +/- 9 M(-1)s(-1)), norethindrone (2215 +/- 76 M(-1) s(-1)) and levonorgestrel (1427 +/- 62 M(-1) s(-1)). Compared to phenolic estrogens (estrone, 17 beta-estradiol, estriol and 17 alpha-ethinylestradiol), the selected progestogen endocrine disruptors reacted far slower with ozone. In the second part of the study, bench-scale experiments were conducted with surface waters spiked with 16 target compounds to assess their oxidative removal using ozone and determine if bench-scale results would accurately predict full-scale removal data. overall, the data provided evidence that ozone is effective for removing trace organic contaminants from water with ozone doses typically applied in drinking water treatment. Ozonation. removed over 80% of caffeine, pharmaceuticals and endocrine disruptors within the CT value of about 2 mg min L(-1). As expected, pesticides were found to be the most recalcitrant compounds to oxidize. Caffeine can be used as an indicator compound to gauge the efficacy of ozone treatment. (C) 2009 Elsevier Ltd. All rights reserved.


Drinking water; Ozone; Caffeine; Pharmaceuticals; Endocrine disruptors; Pesticides

Published in

Water Research
2009, Volume: 43, number: 18, pages: 4707-4717

    Sustainable Development Goals

    SDG6 Ensure availability and sustainable management of water and sanitation for all
    SDG3 Ensure healthy lives and promote well-being for all at all ages

    UKÄ Subject classification

    Environmental Sciences

    Publication identifier


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