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Research article - Peer-reviewed, 2013

Serum Serotonin Concentration Is Associated with Severity of Myxomatous Mitral Valve Disease in Dogs

Bersås Ljungvall, Ingrid; Höglund, Katja; Lilliehöök, Inger; Oyama, Mark; Tidholm, Anna; Tvedten, Harold; Häggström, Jens


The finding of higher serum 5-HT concentrations in dogs of breeds predisposed to the early onset of MMVD (CKCS) and dogs with mild MMVD suggests that alterations in 5-HT signaling might play a role in progression of early stages of MMVD.


Platelet function; Canine myxomatous disease; Cardiology; Valvular disease

Published in

Journal of Veterinary Internal Medicine
2013, Volume: 27, number: 5, pages: 1105-1112