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Research article - Peer-reviewed, 2013

Short-Term Hemodynamic and Neuroendocrine Effects of Pimobendan and Benazapril in Dogs with Myxomatous Mitral Valve Disease and Congestive Heart Failure

Häggström, Jens; Lord, Peter; Höglund, Katja; Bersås Ljungvall, Ingrid; Jöns, Olaf; Kvart, Clarence; Hansson, Kerstin

Abstract

Conclusions and Clinical ImportancePimobendan improves short-term cardiac function more than benazepril in dogs with CHF caused by MMVD. Pimobendan treatment enables the heart to work at smaller end-systolic and diastolic dimensions while maintaining adequate forward stroke volume. Some of the treatment responses found in neuroendocrine profile might have therapeutic relevance.

Keywords

Canine; Heart rate; Heart size; Mitral regurgitation; Therapy

Published in

Journal of Veterinary Internal Medicine
2013, volume: 27, number: 6, pages: 1452-1462
Publisher: WILEY-BLACKWELL

Authors' information

Häggström, Jens
Swedish University of Agricultural Sciences, Department of Clinical Sciences
Lord, Peter
Swedish University of Agricultural Sciences, Department of Clinical Sciences
Höglund, Katja
Swedish University of Agricultural Sciences, Department of Anatomy, Physiology and Biochemistry (AFB)
Ljungvall, Ingrid
Swedish University of Agricultural Sciences, Department of Clinical Sciences
Jöns, Olaf
Kvart, Clarence
Swedish University of Agricultural Sciences, Department of Anatomy, Physiology and Biochemistry (AFB)
Hansson, Kerstin
Swedish University of Agricultural Sciences, Department of Clinical Sciences

UKÄ Subject classification

Cardiac and Cardiovascular Systems

Publication Identifiers

DOI: https://doi.org/10.1111/jvim.12217

URI (permanent link to this page)

https://res.slu.se/id/publ/51700