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Research article2013Peer reviewedOpen access

Short-Term Hemodynamic and Neuroendocrine Effects of Pimobendan and Benazapril in Dogs with Myxomatous Mitral Valve Disease and Congestive Heart Failure

Häggström, Jens; Lord, Peter; Höglund, Katja; Bersås Ljungvall, Ingrid; Jöns, Olaf; Kvart, Clarence; Hansson, Kerstin


Conclusions and Clinical ImportancePimobendan improves short-term cardiac function more than benazepril in dogs with CHF caused by MMVD. Pimobendan treatment enables the heart to work at smaller end-systolic and diastolic dimensions while maintaining adequate forward stroke volume. Some of the treatment responses found in neuroendocrine profile might have therapeutic relevance.


Canine; Heart rate; Heart size; Mitral regurgitation; Therapy

Published in

Journal of Veterinary Internal Medicine
2013, Volume: 27, number: 6, pages: 1452-1462