Kradolfer, David
- Department of Plant Biology, Swedish University of Agricultural Sciences
- Swiss Federal Institute of Technology (ETH Zürich)
Research article2013Peer reviewedOpen access
An Imprinted Gene Underlies Postzygotic Reproductive Isolation in Arabidopsis thaliana
Kradolfer, David; Wolff, Philip; Jiang, Hua; Siretskiy, Alexey; Köhler, Claudia
Abstract
Postzygotic reproductive isolation in response to interploidy hybridizations is a well-known phenomenon in plants that forms a major path for sympatric speciation. A main determinant for the failure of interploidy hybridizations is the endosperm, a nutritious tissue supporting embryo growth, similar to the functional role of the placenta in mammals. Although it has been suggested that deregulated imprinted genes underpin dosage sensitivity of the endosperm, the molecular basis for this phenomenon remained unknown. In a genetic screen for suppressors of trip-bid seed abortion, we have identified the paternally expressed imprinted gene ADMETOS (ADM). Here, we present evidence that increased dosage of ADM causes triploid seed arrest. A large body of theoretical work predicted that deregulated imprinted genes establish the barrier to interploidy hybridization. Our study thus provides evidence strongly supporting this hypothesis and generates the molecular basis for our understanding of postzygotic hybridization barriers in plants.
Published in
Developmental Cell
2013, volume: 26, number: 5, pages: 525-535
Publisher: CELL PRESS
SLU Authors
Wolff, Philip
- Department of Plant Biology, Swedish University of Agricultural Sciences
- Swiss Federal Institute of Technology (ETH Zürich)
- Department of Plant Biology, Swedish University of Agricultural Sciences
Jiang, Hua
- Department of Plant Biology, Swedish University of Agricultural Sciences
- Department of Plant Biology, Swedish University of Agricultural Sciences
Siretskiy, Alexey
- Department of Plant Biology, Swedish University of Agricultural Sciences
- Department of Plant Biology, Swedish University of Agricultural Sciences
Köhler, Claudia
- Department of Plant Biology, Swedish University of Agricultural Sciences
- Department of Plant Biology, Swedish University of Agricultural Sciences
UKÄ Subject classification
Plant Biotechnology
Developmental Biology
Publication identifier
- DOI: https://doi.org/10.1016/j.devcel.2013.08.006
Permanent link to this page (URI)
https://res.slu.se/id/publ/52900