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Research article - Peer-reviewed, 2013

Oxygenation and plasma endothelin-1 concentrations in healthy horses recovering from isoflurane anaesthesia administered with or without pulse-delivered inhaled nitric oxide

Grubb, Tamara; Edner, Anna; Frendin, Jan; Funkquist, Pia; Ryden, Anneli; Nyman, Görel; Grubb, Tamara


Conclusions and Clinical Relevance Delivery of iNO to healthy horses during anaesthesia results in better arterial and venous oxygenation and V/Q matching (as determined by lower (Q) over dots/(Q) over dott) and lower ET-1 concentrations throughout a 30-minute anaesthetic recovery period.


anaesthesia; endothelin-1; horse; nitric oxide; oxygenation; shunt; ventilation-perfusion matching

Published in

Veterinary Anaesthesia and Analgesia
2013, Volume: 40, number: 6, pages: E9-E18