Body Temperature during Hibernation Is Highly Correlated with a Decrease in Circulating Innate Immune Cells in the Brown Bear (Ursus arctos): A Common Feature among Hibernators?

Saldo, Berolla; Evans, Alina L; Arnemo, Jon; Fröbert, Ole; Särndahl, Eva; Blanc, Stephane

doi:10.7150/ijms.4476

Research article2013Peer reviewedOpen access

Body Temperature during Hibernation Is Highly Correlated with a Decrease in Circulating Innate Immune Cells in the Brown Bear (Ursus arctos): A Common Feature among Hibernators?

Saldo, Berolla; Evans, Alina L; Arnemo, Jon; Fröbert, Ole; Särndahl, Eva; Blanc, Stephane

Abstract

Conclusions: Bears have fewer innate immune cells in circulation during hibernation, which may represent a suppressed innate immune system. Across species comparison suggests that, both in small and large hibernators, Tb is the main driver of immune function regulation during winter dormancy. The lack of a difference in lymphocyte counts in this context requires further investigations.

Keywords

Brown bear; Ursus arctos; Hibernation; Innate immunity; Leukocytes; Torpor

Published in

International Journal of Medical Sciences
2013, Volume: 10, number: 5, pages: 508-514
Publisher: IVYSPRING INT PUBL

SLU Authors

Arnemo, Jon
- Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences

UKÄ Subject classification

Other Veterinary Science
Ecology

Publication identifier

DOI: https://doi.org/10.7150/ijms.4476

Permanent link to this page (URI)

https://res.slu.se/id/publ/55282