Uvnäs-Moberg, Kerstin
- Department of Applied Animal Science and Welfare, Swedish University of Agricultural Sciences
Research article2013Peer reviewedOpen access
Plasma oxytocin changes and anti-obsessive response during serotonin reuptake inhibitor treatment: a placebo controlled study
Humble, Mats B.; Uvnäs-Moberg, Kerstin; Engström, Ingemar; Bejerot, Susanne
Abstract
Conclusions: SRIs have highly variable effects on plasma oxytocin between individuals. The associations between baseline oxytocin and OCD severity and between oxytocin changes and treatment response support the notions that oxytocin is involved in OCD pathophysiology, and that the anti-obsessive effects of SRIs are partly exerted through oxytocinergic mechanisms.
Keywords
Obsessive-compulsive disorder; Oxytocin/plasma; Serotonin; Serotonin uptake inhibitors; Treatment response; Randomized controlled trial; Autism spectrum disorder; Placebo response
Published in
BMC Psychiatry
2013, Volume: 13
Publisher: BIOMED CENTRAL LTD
SLU Authors
UKÄ Subject classification
Psychiatry
Publication identifier
DOI: https://doi.org/10.1186/1471-244X-13-344
Permanent link to this page (URI)
https://res.slu.se/id/publ/55284