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Research article2013Peer reviewedOpen access

Patients with anaemia can shift from kidney to liver production of erythropoietin as shown by glycoform analysis

Lönnberg, Maria; Garle, Mats; Lönnberg, Lina; Birgegård, Gunnar

Abstract

This glycoform analysis has made it possible to affirm that some anaemic patients can increase their liver-production of EPO. The use of such a method can give better insight into the regulation of non-renal endogenous EPO production, a potential source of EPO intended to replace administration of exogenous EPO. (C) 2013 Elsevier B.V. All rights reserved.

Keywords

EPO; Epoetin; Darbepoetin; Haemodialysis; Lectin chromatography; WGA

Published in

Journal of Pharmaceutical and Biomedical Analysis
2013, Volume: 81-82, pages: 187-192
Publisher: ELSEVIER SCIENCE BV

    UKÄ Subject classification

    Analytical Chemistry

    Publication identifier

    DOI: https://doi.org/10.1016/j.jpba.2013.04.009

    Permanent link to this page (URI)

    https://res.slu.se/id/publ/56192