Patients with anaemia can shift from kidney to liver production of erythropoietin as shown by glycoform analysis

Lönnberg, Maria; Garle, Mats; Lönnberg, Lina; Birgegård, Gunnar

doi:10.1016/j.jpba.2013.04.009

Research article - Peer-reviewed, 2013

Patients with anaemia can shift from kidney to liver production of erythropoietin as shown by glycoform analysis

Lönnberg, Maria; Garle, Mats; Lönnberg, Lina; Birgegård, Gunnar

Abstract

This glycoform analysis has made it possible to affirm that some anaemic patients can increase their liver-production of EPO. The use of such a method can give better insight into the regulation of non-renal endogenous EPO production, a potential source of EPO intended to replace administration of exogenous EPO. (C) 2013 Elsevier B.V. All rights reserved.

Keywords

EPO; Epoetin; Darbepoetin; Haemodialysis; Lectin chromatography; WGA

Published in

Journal of Pharmaceutical and Biomedical Analysis
2013, volume: 81-82, pages: 187-192
Publisher: ELSEVIER SCIENCE BV

Authors' information

Lönnberg, Maria

Uppsala University

Garle, Mats

Karolinska Universitetsdjursjukhuset

Lönnberg, Lina

Swedish University of Agricultural Sciences, Department of Ecology

Birgegård, Gunnar

Uppsala University

UKÄ Subject classification

Analytical Chemistry

Publication Identifiers

DOI: https://doi.org/10.1016/j.jpba.2013.04.009

URI (permanent link to this page)

https://res.slu.se/id/publ/56192