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Research article2013Peer reviewedOpen access

The effects of pulse-delivered inhaled nitric oxide on arterial oxygenation, ventilation-perfusion distribution and plasma endothelin-1 concentration in laterally recumbent isoflurane-anaesthetized horses

Grubb, Tamara; Frendin, Jan; Edner, Anna; Funkquist, Pia; Hedenstierna, Göran; Nyman, Görel

Abstract

Conclusions and Clinical Relevance PiNO delivered in the initial portion of the inspiration effectively relieves hypoxaemia in anaesthetized horses by improving ((V) over dot(A)/(Q) over dot) matching and decreasing ((Q) over dots/(Q) over dott) without affecting ET-1.

Keywords

anaesthesia; endothelin-1; gas exchange; horse; hypoxaemia; MIGET; nitric oxide; (Q) over dots/(Q) over dott; shunt; (V) over dot(A)/(Q) over dot

Published in

Veterinary Anaesthesia and Analgesia
2013, Volume: 40, number: 6, pages: E19-E30
Publisher: WILEY-BLACKWELL