Abstract

Bioassay-guided fractionation of cell-free culture supernatants of the bacterium MA250 yielded three bioactive compounds (1-3). Compound 1 was identified as the unsaturated fatty acid gamma-lactone piliferolide A, compound 2 as the not previously described open acid form of 1, and 3 as the compound SB-253514, which is an imide of a 3--rhamnosyl fatty acid and a bicyclic carbamate. All three compounds displayed moderate activity towards the pink snow mould causing pathogen , and may thus contribute to the previously observed biological control of this strain on on wheat. Compound 1 further exhibited activity towards the human pathogen , while compound 3 showed antifungal as well as antibacterial activity.

Keywords

Antibiosis; Antifungal; Biocontrol; Microbial antagonism; Microdochium nivale

Published in

BioControl
2012, Volume: 57, number: 3, pages: 463-469
Publisher: SPRINGER

SLU Authors

• Andersson, Pierre

  • Department of Molecular Sciences, Swedish University of Agricultural Sciences
    

• Broberg, Anders

  • Department of Molecular Sciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Agricultural Science


Publication identifier

DOI: https://doi.org/10.1007/s10526-011-9411-5

Permanent link to this page (URI)

https://res.slu.se/id/publ/56370