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Research article - Peer-reviewed, 2014

Sesquiterpenes from the saprotrophic fungus Granulobasidium vellereum (Ellis 82 Cragin) Julich

Nord, Christina; Menkis, Audrius; Lendel, Christofer; Vasaitis, Rimvydas; Broberg, Anders


Twelve sesquiterpenes comprising either the protoilludane or the rare cerapicane carbon skeletons were obtained from the saprotrophic wood decomposing fungus Granulobasidium vellereum; 2a-hydroxycoprinolone (1), 3-hydroxycoprinolone (2), coprinolone dial B (3), granulodiene A (4), granulodiene B (5), granulone A (6), 8-deoxy-4a-hydroxytsugicoline B (7), granulone B (8), demethylgranulone (9), cerapicolene (10), as well as the known compounds radudiol and Delta(6)-coprinolone. The structures were determined using spectroscopic methods and biosynthetic considerations. Granulone A had growth stimulating effect on the total elongation of lettuce. seedlings. None of the isolated compounds showed any antifungal effect. (C) 2014 Elsevier Ltd. All rights reserved.


Granulobasidium vellereum; Structural elucidation; Sesquiterpenes; Protoilludane; Cerapicane; Growth promotor

Published in

2014, Volume: 102, pages: 197-204

      SLU Authors

    • Nord, Christina

      • The Department of Chemistry and Biotechnology, Swedish University of Agricultural Sciences