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Research article2003Peer reviewedOpen access

Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14

Sjogren J, Magnusson J, Broberg A, Schnurer J, Kenne L

Abstract

We report the identification and chemical characterization of four antifungall substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 mug ml(-1)

Published in

Applied and Environmental Microbiology
2003, Volume: 69, number: 12, pages: 7554-7557
Publisher: AMER SOC MICROBIOLOGY