Jansson, Janet
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
- Lawrence Berkeley National Laboratory (Berkeley Lab)
Abstract
Although it is known that antibiotics have short-term impacts on the human microbiome, recent evidence demonstrates that the impacts of some antibiotics remain for extended periods of time. In addition, antibiotic-resistant strains can persist in the human host environment in the absence of selective pressure. Both molecular- and cultivation-based approaches have revealed ecological disturbances in the microbiota after antibiotic administration, in particular for specific members of the bacterial community that are susceptible or alternatively resistant to the antibiotic in question. A disturbing consequence of antibiotic treatment has been the long-term persistence of antibiotic resistance genes, for example in the human gut. These data warrant use of prudence in the administration of antibiotics that could aggravate the growing battle with emerging antibiotic-resistant pathogenic strains.
Published in
Microbiology
2010, volume: 156, number: 11, pages: 3216-3223
Publisher: SOC GENERAL MICROBIOLOGY
SLU Authors
Associated SLU-program
AMR: Bacteria
Global goals (SDG)
SDG3 Good health and well-being
UKÄ Subject classification
Microbiology
Publication identifier
- DOI: https://doi.org/10.1099/mic.0.040618-0
Permanent link to this page (URI)
https://res.slu.se/id/publ/61394