Pielberg, Gerli
- Department of Animal Biosciences, Swedish University of Agricultural Sciences
Abstract
A genome wide search in European Wild Boar x Swedish Yorkshire (W x Y) inter-cross pigs has earlier identified quantitative trait loci (QTL) for leucocyte number and function on porcine chromosomes 1 and 8 (SSC1. and 8). To verify the involvement of these chromosomal regions in the regulation of haematocrit (Hem) and haemoglobin (Hb) levels, leucocyte numbers and in vitro leukocyte functions (mitogen induced proliferation and IL-2 production, virus induced interferon-a production and neutrophil phagocytosis), animals of different genetic backgrounds were analysed. The animals comprised a back-cross sire family (n = 47) of W x Y pigs and six crossbred [Y x Landrace (L)] sire families (n = 191). They were genotyped for 16 genetic markers and an interval analysis was performed. On SSC1, a QTL close to S0082 on the q-arm that influenced numbers of white blood cells in L x Y pigs and numbers of band neutrophils and CD8(+) cells in W x Y pigs was identified (P
Keywords
immune function; KIT; leucocyte numbers; pig; quantitative trait loci
Published in
Animal Genetics
2005, volume: 36, number: 4, pages: 337-345
Publisher: BLACKWELL PUBLISHING
SLU Authors
Andersson, Leif
- Department of Animal Biosciences, Swedish University of Agricultural Sciences
- Department of Animal Biosciences, Swedish University of Agricultural Sciences
Edfors-Lilja, Inger
- Department of Animal Biosciences, Swedish University of Agricultural Sciences
- Department of Animal Biosciences, Swedish University of Agricultural Sciences
UKÄ Subject classification
Veterinary Science
Animal and Dairy Science
Publication identifier
- DOI: https://doi.org/10.1111/j.1365-2052.2005.01315.x
Permanent link to this page (URI)
https://res.slu.se/id/publ/6204