A multivariate NIR study of skin alterations in diabetic patients as compared to control subjects

Geladi, Paul; Nyström, Josefina; Eriksson, JW; Nilsson, A.; Lithner, F; Lindholm-Sethson, B

doi:10.1255/jnirs.282

Research article2000Peer reviewed

A multivariate NIR study of skin alterations in diabetic patients as compared to control subjects

Geladi, Paul; Nyström, Josefina; Eriksson, JW; Nilsson, A.; Lithner, F; Lindholm-Sethson, B

Abstract

A group of 15 diabetic persons with different degrees of diabetes complications, including skin changes, was studied by Fourier Transform Near Infrared (FT-NIR) spectroscopy. Skin reflectance spectra were measured with a fibre-optic probe in four locations (sites): hand, arm, leg and foot. For reference, a group of 28 healthy controls was also measured, Multivariate analysis of the NIR spectra obtained shows a high potential for classification and discrimination of the skin conditions. Valuable indications for future experiments can be observed.

Keywords

FT-NIR; fibre-optic probe; PCA; PLS-DA; skin changes; diabetes

Published in

Journal of Near Infrared Spectroscopy
2000, Volume: 8, number: 4, pages: 217-227
Publisher: N I R PUBLICATIONS

A multivariate NIR study of skin alterations in diabetic patients as compared to control subjects

Abstract

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