Månsson, Johan
- Department of Ecology, Swedish University of Agricultural Sciences
Research article2015Peer reviewed
IgA deficiency in wolves from Canada and Scandinavia
Frankowiack, Marcel; Olsson, Mia; Cluff, H. Dean; Evans, Alina L.; Hellman, Lars; Månsson, Johan; Arnemo, Jon; Hammarström, Lennart
Abstract
Immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in both humans and selected breeds of domestic dogs. In both species, IgAD is associated with recurrent infections and immune mediated diseases. Previous results imply that IgAD is also common in the wild ancestor of domestic dogs, the gray wolf. Here, we report that serum IgA concentrations are significantly different in Scandinavian and Canadian wolves (p =3.252e-15) with an increased prevalence for IgAD in Scandinavian wolves (60%), which is as high as those found in high-risk dog breeds. (C) 2014 Elsevier Ltd. All rights reserved.
Keywords
Serum IgA concentrations; IgA deficiency; Dog; Wolf
Published in
Developmental and Comparative Immunology
2015, Volume: 50, number: 1, pages: 26-28
Arnemo, Jon
- Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences
- Hedmark University College
- Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences
SLU Authors
UKÄ Subject classification
Forest Science
Other Veterinary Science
Ecology
Publication identifier
DOI: https://doi.org/10.1016/j.dci.2014.12.009
Permanent link to this page (URI)
https://res.slu.se/id/publ/63692