Lindqvist, Roland
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
- National Food Agency
This study tested the hypothesis that sensitivity of Escherichia coli to lactic acid at concentrations relevant for fermented sausages ( pH 4.6, 150 mM lactic acid, a(w) = 0.92, temperature = 20 or 27 degrees C) increases with increasing growth rate. For E. coli strain 683 cultured in TSB in chemostat or batch, subsequent inactivation rates when exposed to lactic acid stress increased with increasing growth rate at harvest. A linear relationship between growth rate at harvest and inactivation rate was found to describe both batch and chemostat cultures. The maximum difference in T-90, the estimated times for a one-log reduction, was 10 hours between bacteria harvested during the first 3 hours of batch culture, that is, at different growth rates. A 10-hour difference in T-90 would correspond to measuring inactivation at 33 degrees C or 45 degrees C instead of 37 degrees C based on relationships between temperature and inactivation. At similar harvest growth rates, inactivation rates were lower for bacteria cultured at 37 degrees C than at 15-20 degrees C. As demonstrated for E. coli 683, culture conditions leading to variable growth rates may contribute to variable lactic acid inactivation rates. Findings emphasize the use and reporting of standardised culture conditions and can have implications for the interpretation of data when developing inactivation models.
Microbiology; Acid stress response
BioMed Research International
2014, article number: 471317
Publisher: HINDAWI PUBLISHING CORPORATION
Other Health Sciences
https://res.slu.se/id/publ/63880