Immunohistochemical investigation into the distribution pattern of myoepithelial cells in the bovine mammary gland

Abstract

The distribution pattern of myoepithelial cells in the bovine mammary gland was investigated by an immunohistochemical technique, using monoclonal antibodies against cytokeratins 5, 6 and 18 and cytokeratins 8 and 14 and against a-smooth-muscle actin filaments. Myoepithelial cells were shown to be present as a continuous basal cell layer in the intralobular ducts, as discontinuous cell rows in the basal cell layer of the interlobular ducts, and as single cells dispersed in the basal cell layer of the quarter cisterns, while they were apparently absent in the teat cisterns. Unlike the case with myoepithelial cells of the human breast, anticytokeratin 14 was less specific as a marker of bovine myoepithelial cells than was anti-cz-smooth-muscle actin.

Published in

Journal of Dairy Research
1997, volume: 64, number: 2, pages: 197-205
Publisher: CAMBRIDGE UNIV PRESS

SLU Authors

• Hellmén, Eva

  • Department of Pathology, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Pathobiology

Publication identifier

• DOI: https://doi.org/10.1017/S0022029997002148

Permanent link to this page (URI)

https://res.slu.se/id/publ/64782