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Research article - Peer-reviewed, 2014

Dietary glucose regulates yeast consumption in adult Drosophila males

Lebreton, Sebastien; Witzgall, Peter; Olsson, Marie; Becher, Paul

Abstract

The adjustment of feeding behavior in response to hunger and satiety contributes to homeostatic regulation in animals. The fruit fly Drosophila melanogaster feeds on yeasts growing on overripe fruit, providing nutrients required for adult survival, reproduction and larval growth. Here, we present data on how the nutritional value of food affects subsequent yeast consumption in Drosophila adult males. After a period of starvation, flies showed intensive yeast consumption. In comparison, flies stopped feeding after having access to a nutritive cornmeal diet. Interestingly, dietary glucose was equally efficient as the complex cornmeal diet. In contrast, flies fed with sucralose, a non-metabolizable sweetener, behaved as if they were starved. The adipokinetic hormone and insulin-like peptides regulate metabolic processes in insects. We did not find any effect of the adipokinetic hormone pathway on this modulation. Instead, the insulin pathway was involved in these changes. Flies lacking the insulin receptor (InR) did not respond to nutrient deprivation by increasing yeast consumption. Together these results show the importance of insulin in the regulation of yeast consumption in response to starvation in adult D. melanogaster males.

Keywords

adipokinetic hormone; feeding behavior; insulin; starvation; sugar

Published in

Frontiers in Physiology
2014, volume: 5, article number: 504

Authors' information

Lebreton, Sebastien
Swedish University of Agricultural Sciences, Department of Plant Protection Biology
Swedish University of Agricultural Sciences, Department of Plant Protection Biology
Swedish University of Agricultural Sciences, Department of Plant Breeding
Swedish University of Agricultural Sciences, Department of Plant Protection Biology

UKÄ Subject classification

Behavioral Sciences Biology
Ecology
Zoology

Publication Identifiers

DOI: https://doi.org/10.3389/fphys.2014.00504

URI (permanent link to this page)

https://res.slu.se/id/publ/65995