No Evidence for the Effect of MHC on Male Mating Success in the Brown Bear

Abstract

Mate choice is thought to contribute to the maintenance of the spectacularly high polymorphism of the Major Histocompatibility Complex (MHC) genes, along with balancing selection from parasites, but the relative contribution of the former mechanism is debated. Here, we investigated the association between male MHC genotype and mating success in the brown bear. We analysed fragments of sequences coding for the peptide-binding region of the highly polymorphic MHC class I and class II DRB genes, while controlling for genome-wide effects using a panel of 18 microsatellite markers. Male mating success did not depend on the number of alleles shared with the female or amino-acid distance between potential mates at either locus. Furthermore, we found no indication of female mating preferences for MHC similarity being contingent on the number of alleles the females carried. Finally, we found no significant association between the number of MHC alleles a male carried and his mating success. Thus, our results provided no support for the role of mate choice in shaping MHC polymorphism in the brown bear.

Published in

PLoS ONE
2014, volume: 9, number: 12, article number: e113414
Publisher: PUBLIC LIBRARY SCIENCE

SLU Authors

• Kindberg, Jonas

  • Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Evolutionary Biology
Genetics and Genomics

Publication identifier

• DOI: https://doi.org/10.1371/journal.pone.0113414

Permanent link to this page (URI)

https://res.slu.se/id/publ/67128