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Research article2016Peer reviewed

Promotion of wound healing by Plantago major L. leaf extracts – ex-vivo experiments confirm experiences from traditional medicine

Zubair, Muhammad; Nybom, Hilde; Lindholm, Christina; Brandner, Johanna M.; Rumpunen, Kimmo

Abstract

The wound-healing properties of Plantago major L. (plantain) were evaluated using an ex-vivo porcine wound-healing model. Ethanol- and water-based extracts were prepared from greenhouse-grown and freeze-dried leaves of P. major. Both types of extracts stimulated wound healing in porcine skin, but the ethanol-based extracts had a somewhat stronger effect. A concentration of 1.0 mg/mL (on dry weight basis) produced the best results for both types of extracts.

Keywords

common plantain; Plantaginaceae; Plantamajoside; Polyphenols

Published in

Natural Product Research
2016, Volume: 30, number: 5, pages: 622-624