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Research article - Peer-reviewed, 2015

Prevalence of and factors associated with Brucella sero-positivity in cattle in urban and peri-urban Gulu and Soroti towns of Uganda

Rwabiita Mugizi, Denis; Boqvist, Sofia; Nasinyama, George; Waiswa, Charles; Ikwap, Kokas; Rock, Kim; Lindahl, Elisabeth; Magnusson, Ulf; Erume, Joseph;

Abstract

Brucellosis is a key zoonosis of major public health, animal welfare and economic significance, and is endemic in livestock in Uganda. A cross-sectional epidemiological study was carried out to estimate the sero-prevalence of brucellosis and identify factors associated with sero-positivity in cattle in urban and pen-urban Gulu and Soroti towns of Northern and Eastern Uganda, respectively. A total of 1007 sera and data on biologically plausible risk factors from 166 herds and their spatial locations, were collected from cattle reared in urban and pen-urban Gulu and Soroti towns of Uganda. The sera were analyzed using indirect ELISA and sero-positive reactors confirmed by competitive ELISA. Multivariable models were used to investigate for risk factors. The overall animal-level and herd-level sero-prevalence was 7.5% (76/1007, 95% Confidence Interval (CI): 6.15-9.4%) and 27.1% (45/166, 95% CI: 20.9-34.3%), respectively. Herd-level sero-prevalence was significantly (P<0.001) higher in Soroti than Gulu. In Gulu town, sero-positivity increased with an increase in herd size (P=0.03) and age (P=0.002), and was higher in cattle brought in from western Uganda (P<0.0001). In Soroti town, introduction of new cattle into a herd was significantly (P=0.027) associated with herd sero-positivity. There was a geographically differential risk (clustering) of Brucella sero- positivity in herds in Soroti, while sero-positivity was homogeneously distributed in Gulu. The data highlight brucellosis occurrence and major risk factors for its transmission in cattle in urban and pen-urban areas.

Keywords

brucellosis; risk factor; sero-positivity; Uganda; urban and peri-urban cattle

Published in

Journal of Veterinary Medical Science

2015, volume: 77, number: 5, pages: 557-564
Publisher: JAPAN SOC VET SCI

Authors' information

Rwabiita Mugizi, Denis
Makerere University
Nasinyama, George
Makerere University
Waiswa, Charles
Makerere University
Ikwap, Kokas
Makerere University
Rock, Kim
Swedish University of Agricultural Sciences, Department of Biomedical Science and Veterinary Public Health
Lindahl, Elisabeth (Rajala, Elisabeth)
Swedish University of Agricultural Sciences, Department of Clinical Sciences
Swedish University of Agricultural Sciences, Department of Clinical Sciences
Erume, Joseph
Makerere University

Sustainable Development Goals

SDG3 Good health and wellbeing

UKÄ Subject classification

Clinical Science
Medical Bioscience

Publication Identifiers

DOI: https://doi.org/10.1292/jvms.14-0452

URI (permanent link to this page)

https://res.slu.se/id/publ/69407