Skip to main content
Research article - Peer-reviewed, 2005

Strain- and genotype-specific differences in virulence of Paenibacillus larvae subsp larvae, a bacterial pathogen causing American foulbrood disease in honeybees

Genersch E, Ashiralieva A, Fries I


Virulence variations of Paenibacillus larvae subsp. larvae, the causative agent of American foulbrood disease of honeybees, were investigated by analysis of 16 field isolates of this pathogen, belonging to three previously characterized genotypes, as well as the type strain (ATCC 9545) of P. larvae subsp. larvae, with exposure bioassays. We demonstrated that the strain-specific 50% lethal concentrations varied within an order of magnitude and that differences in amount of time for the pathogen to kill 100% of the infected hosts (LT100) correlated with genotype. One genotype killed rather quickly, with a mean LT100 of 7.8 +/- 1.7 days postinfection, while the other genotypes acted more slowly, with mean LT(100)s of 11.2 +/- 0.8 and 11.6 +/- 0.6 days postinfection

Published in

Applied and Environmental Microbiology
2005, Volume: 71, number: 11, pages: 7551-7555

    SLU Authors

    • Fries, Ingemar

      • Department of Entomology, Swedish University of Agricultural Sciences

    UKÄ Subject classification

    Animal and Dairy Science
    Veterinary Science

    Publication Identifiers


    Permanent link to this page (URI)