Anomalous adsorption of biomolecules on a Zn-based metal-organic framework obtained via a facile room-temperature route

Abstract

Herein, we report a new method for the crystal growth of two Zn-based MOFs at room temperature (known MOF-5 and a new modification of [{Zn-2(TBAPy)(H2O)(2)}center dot 3.5DEF](n) (1)) by employing slow diffusion conditions. Employing both Zn-based MOFs with different pore morphology made it possible to discover an anomalous adsorption of L-histidine in 1 of up to 24.3 x 10(15) molecules cm(-2) at 25 degrees C. This is one of the first reports aimed not only at describing a new method for the targeted formation of crystalline MOFs and coordination polymers, but also at demonstrating the use of Zn-based MOFs as potential drug delivery materials, with highly effective adsorption of L-histidine given herein as an example.

Published in

Chemical Communications
2015, volume: 51, number: 100, pages: 17764-17767
Publisher: ROYAL SOC CHEMISTRY

SLU Authors

• Seisenbaeva, Gulaim

  • The Department of Chemistry and Biotechnology, Swedish University of Agricultural Sciences
    

• Kessler, Vadim

  • Department of Molecular Sciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Biomaterials Science
Materials Chemistry
Inorganic Chemistry

Publication identifier

• DOI: https://doi.org/10.1039/c5cc07808c

Permanent link to this page (URI)

https://res.slu.se/id/publ/75427