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Book chapter2016

Porcine Rubulavirus

Berg, Mikael; Cuevas-Romero, Sandra; Moreno-Lopez, Jorge

Abstract

This pig disease appeared in the early 1980s, but problems associated with the virus still remain. The dense population of pigs in the Mexican states of Michoacan, Jalisco and Guanajuato are the main focus of porcine rubulavirus may infection. The epidemiology of this disease is not fully clear. Bats may be a natural reservoir and may spread the virus to pigs, as has been reported for other emerging paramyxoviruses, and may explain why the virus seems to be localized. However, it is also clear that the virus circulates in pigs and so various trade precautions are important. In terms of viral genetic variation, the different isolates that have been found vary between years, but not extensively. In fact, some very recent isolates are very similar to old prototype isolates from the early 1980s. However, information on this is scarce and this needs to be studied in more detail. A least three genetic variants, based on the sequence of the haemagglutinine-neuraminidose gene, do circulate, but more may be found when the other genes and more isolates are studied. One obvious way to control this disease would be to develop an effective vaccine. There are some vaccine concepts that have been tested and can be put into field practice, and these are described and discussed in this chapter.

Published in

Title: Mononegaviruses of Veterinary Importance, Volume 2
ISBN: 9781780644172
Publisher: CABI