Research article - Peer-reviewed, 2016
Risk factors associated with Campylobacter detected by PCR in humans and animals in rural Cambodia
Osbjer, Kristina; Boqvist, Sofia; Seng, Sokerya; Chheng, K.; San, S.; Davun, H.; Rautelin, H.; Magnusson, UlfAbstract
Campylobacter are worldwide-occurring zoonotic bacteria, with the species Campylobacter jejuni and C. coli commonly associated with diarrhoea in children in low-income countries. In this cross-sectional study, the prevalence of C. jejuni and C. coli in human and livestock faecal samples was detected by PCR and zoonotic risk factors associated with human Campylobacter positivity were identified. In total 681 humans and 753 livestock (chickens, ducks, pigs, cattle) from 269 households were sampled. Children aged < 16 years were more frequently Campylobacter positive (19%) than adults (8%) and multilevel logistic models revealed that human C. jejuni positivity was associated with the following household practices: home-slaughtering [odds ratio (OR) 2.4, P = 0.01], allowing animals access to sleeping and food preparation areas (OR 2.8, P = 0.02), and eating undercooked meat (OR 6.6, P = 0.05), while frequent consumption of beef was protective (OR 0.9, P = 0.05). Associations were stronger for home-slaughtering (OR 4.9, P = 0.004) with C. jejuni infection in children only. Campylobacter was highly prevalent in pigs (72%) and chickens (56%) and risk factors associated with human Campylobacter positivity were identified throughout the meat production chain. The findings underline the importance of studying source attributions throughout the production chain and the need for upgraded understanding of Campylobacter epidemiology in low-income countries.Keywords
Epidemiology; household practice; prevalence; rural household; zoonosisPublished in
Epidemiology and Infection2016, volume: 144, number: 14, pages: 2979-2988
Publisher: CAMBRIDGE UNIV PRESS
Authors' information
Swedish University of Agricultural Sciences, Department of Clinical Sciences
Swedish University of Agricultural Sciences, Department of Biomedical Science and Veterinary Public Health
Seng, Sokerya
Centre for Livestock and Agriculture Development (CeLAgrid)
Chheng, K.
National Institute of Public Health
San, S.
National Veterinary Research Institute (NaVRI)
Davun, H.
National Veterinary Research Institute (NaVRI)
Rautelin, H.
Uppsala University
Swedish University of Agricultural Sciences, Department of Clinical Sciences
UKÄ Subject classification
Pathobiology
Publication Identifiers
DOI: https://doi.org/10.1017/S095026881600114X
URI (permanent link to this page)
https://res.slu.se/id/publ/80841