Borgefors, Gunilla
- Centre for Image Analysis, Swedish University of Agricultural Sciences
Conference paper2005Peer reviewed
Shape based identification of proteins in volume images
Sintorn IM, Borgefors G
Abstract
A template based matching method, adapted to the application of identifying individual proteins of a certain kind in volume images, is presented. Grey-level and gradient megnitude information is combined in the watershed algorithm to extract stable borders. These are used in a subsequent hierarchical matching algorithm. The matching algorithm uses a distance transform to serach for local best fits between the edges of a template and edges in the underlying image. It is embedded in a resolution pyramid to decrease the risk of getting stuck in false local minima. This method makes it possible to find proteins attached to other proteins, or proteins appearing as split into parts in the images. It also decreases the amount of human interaction m´needed for identifying individual proteins of the searched kind. The method is demonstrated on a set of three volume images of the antibody IgG in solution
Published in
Lecture Notes in Computer Science
2005, volume: 3540, pages: 253-262
Conference
14th Scandinavian Conference on Image Analysis, SCIA 2005
SLU Authors
Permanent link to this page (URI)
https://res.slu.se/id/publ/8357