Abstract

A combination of NOESY and ROESY experiments show that the higher stabilities (T(m)) of phenazine tethered matched (2) and G-A mismatched (4) DNA duplexes are due to the decrease of the exchange-rate (i.e. increase of the life-time) of the imino-protons and the reduced water activity in their minor grooves compared to their non-tethered counterparts (1) and (3).

Published in

Nucleic Acids Research
1993, Volume: 21, number: 18, pages: 4246-4252
Publisher: OXFORD UNIV PRESS UNITED KINGDOM

UKÄ Subject classification

Structural Biology


Publication identifier

DOI: https://doi.org/10.1093/nar/21.18.4246

Permanent link to this page (URI)

https://res.slu.se/id/publ/83881