Biomimetic Hydroxyapatite Growth on Functionalized Surfaces of Ti-6Al-4V and Ti-Zr-Nb Alloys

Abstract

A biomimetic approach for coating titanium-containing alloys with hydroxyapatite (HA) is reported in the article. Two types of Ti-containing alloys were chosen as an object for coating: Ti-6Al-4V (recommended for orthopedic application) and a novel highly biocompatible Ti-Zr-Nb alloy, with good mechanical compatibility due to a modulus that is more close to that of human bones (E a parts per thousand aEuro parts per thousand 50 GPa instead of 110 GPa in Ti-6Al-4V). Coating process was carried out in a 10x-concentrated simulated body fluid (SBF)-synthetic analog of human body plasma. The effect of oxidized and carboxylated alloy surface on formation of biomimetic hydroxyapatite has been studied. By XRD, we found influence of thermal conditions on HA crystal formation and size. SEM images and Fourier transform infrared confirmed that hydroxyapatite with different morphology, crystallinity, and Ca/P ratio formed on metallic surfaces. X-ray photoelectron spectroscopy showed that in the Ti-6AL-4V sample the observed Ca/P ratio reach 0.97, whereas in the Ti-Zr-Nb sample the observed Ca/P ratio reach 1.15.

Keywords

Biomimetic hydroxyapatite; Biocompatible titanium alloys; Ti-6Al-4V; Ti-Zr-Nb; Simulated body fluid

Published in

Nanoscale Research Letters
2015, Volume: 10, article number: 338
Publisher: SPRINGER

UKÄ Subject classification

Inorganic Chemistry


Publication identifier

DOI: https://doi.org/10.1186/s11671-015-1017-x

Permanent link to this page (URI)

https://res.slu.se/id/publ/84548