Abstract

The present study investigated the pituitary oestrogen (ER) and progesterone (PR) receptor concentrations in ewes during the oestrous cycle in the breeding season (n= 19), and in anoestrous ewes treated with gonadotrophin-releasing hormone (GnRH) (n= 11) and anoestrous ewes treated with progesterone + GnRH (n= 11). The pituitary ER and PR concentrations at the expected time of ovulation and in the early and late luteal phases were measured by binding assay. The pattern of pituitary ER and PR concentrations in the progesterone + GnRH-treated ewes resembled the pattern found during the normal oestrous cycle, with ER and PR concentrations decreasing from the time of ovulation to the early luteal phase. In contrast, in ewes treated with GnRH alone, ER and PR concentrations increased in the early luteal phase, which may increase the inhibitory effects of steroid hormones on luteinising hormone secretion, ultimately leading to the development of subnormal luteal phases

Published in

Reproduction, Fertility and Development
2005, volume: 17, number: 7, pages: 721-726
Publisher: C S I R O PUBLISHING

Authors' information