Abstract

This paper describes the development and validation of the first fully automated method, based on on-line solid phase extraction-liquid chromatography-tandem mass spectrometry (on line-SPE-LC-MS/MS), for the determination of UV filters (UV F) and transformation products, with a wide range of physicochemical properties. The developed method was validated and applied to the analysis of the selected compounds in river water (RW), groundwater (GW), influent and effluent wastewater (IWW and EWW). Comparing with the off-line methodologies published so far the presented method provides several advantages including a shorter extraction time, lower sample volume and minimum manipulation. Low limits of detection were achieved for all the studied matrices, <3 ng/L (GW), <3.5 ng/L (RW), <4 ng/L (EWW) and <10 ng/L (IWW), allowing a reliable and accurate quantification of the analytes at trace level. SPE optimization and critical aspects associated with the trace level determination of the target compounds (e.g. matrix effects) have been also considered and discussed. The method was successfully applied to the analysis of the UV F in five real water samples of each considered matrix, being the first time that these compounds were determined in GW. (C) 2013 Elsevier B.V. All rights reserved.

Keywords

UV filters; Transformation products; On-line SPE; LC-MS/MS; Water analysis

Published in

Journal of Chromatography A
2013, Volume: 1294, pages: 106-116
Publisher: ELSEVIER SCIENCE BV

UKÄ Subject classification

Analytical Chemistry


Publication identifier

DOI: https://doi.org/10.1016/j.chroma.2013.04.037

Permanent link to this page (URI)

https://res.slu.se/id/publ/87427