Research article2009Peer reviewedOpen access
In silico analysis of promoter regions from cold-induced genes in rice (Oryza sativa L.) and Arabidopsis thaliana reveals the importance of combinatorial control
Lindlof, Angelica; Brautigam, Marcus; Chawade, Aakash; Olsson, Olof; Olsson, Bjorn
Abstract
Motivation: Cold acclimation involves a number of different cellular processes that together increase the freezing tolerance of an organism. The DREB1/CBFs are transcription factors (TFs) that are prominent in the regulation of cold responses in Arabidopsis thaliana, rice and many other crops. We investigated if the expression of DREB1/CBFs and co-expressed genes relies on combinatorial control by several TFs. Our results support this notion and indicate that methods for studying the regulation of complex cellular processes should include identification of combinations of motifs, in addition to searching for individual overrepresented binding sites.
Published in
Bioinformatics
2009, Volume: 25, number: 11, pages: 1345-1348
UKÄ Subject classification
Bioinformatics and Systems Biology
Publication identifier
DOI: https://doi.org/10.1093/bioinformatics/btp172
Permanent link to this page (URI)
https://res.slu.se/id/publ/90691