Research article2005Peer reviewed
A family of putative transcription termination factors shared amongst metazoans and plants
Linder, T; Park, CB; Asin-Cayuela, J; Pellegrini, M; Larsson, NG; Falkenberg, M; Samuelsson, T; Gustafsson, CM
Abstract
The human mitochondrial transcription termination factor (mTERF) is involved in the regulation of transcription of the mitochondrial genome. Similarity searches and phylogenetic analysis demonstrate that mTERF is a member of large and complex protein family (the MTERF family) shared amongst metazoans and plants. Interestingly, we identify three novel MTERF genes in vertebrates, which all encode proteins with predicted mitochondrial localization. Members of the MTERF family have so far not been detected in fungi, supporting the notion that mitochondrial transcription regulation may have evolved separately in yeast and animal cells.
Keywords
mTERF; transcription; mitochondrion; termination
Published in
Current Genetics
2005, Volume: 48, number: 4, pages: 265-269 Publisher: SPRINGER
UKÄ Subject classification
Bioinformatics and Systems Biology
Publication identifier
DOI: https://doi.org/10.1007/s00294-005-0022-5
Permanent link to this page (URI)
https://res.slu.se/id/publ/90880