Skip to main content
Research article - Peer-reviewed, 2017

A Novel QTL for Powdery Mildew Resistance in Nordic Spring Barley (Hordeum vulgare L. ssp. vulgare) Revealed by Genome-Wide Association Study

Bengtsson, Therese; Ahman, Inger; Manninen, Outi; Reitan, Lars; Christerson, Therese; Jensen, Jens Due; Krusell, Lene; Jahoor, Ahmed; Orabi, Jihad


The powdery mildew fungus, Blumeria graminis f. sp. hordei is a worldwide threat to barley (Hordeum vulgare L. ssp. vulgare) production. One way to control the disease is by the development and deployment of resistant cultivars. A genome-wide association study was performed in a Nordic spring barley panel consisting of 169 genotypes, to identify marker-trait associations significant for powdery mildew. Powdery mildew was scored during three years (2012-2014) in four different locations within the Nordic region. There were strong correlations between data from all locations and years. In total four QTLs were identified, one located on chromosome 4H in the same region as the previously identified mlo locus and three on chromosome 6H. Out of these three QTLs identified on chromosome 6H, two are in the same region as previously reported QTLs for powdery mildew resistance, whereas one QTL appears to be novel. The top NCBI BLASTn hit of the SNP markers within the novel QTL predicted the responsible gene to be the 26S proteasome regulatory subunit, RPN1, which is required for innate immunity and powdery mildew-induced cell death in Arabidopsis. The results from this study have revealed SNP marker candidates that can be exploited for use in marker-assisted selection and stacking of genes for powdery mildew resistance in barley.


Blumeria graminis f. sp hordei; mlo; GWAS; Hordeum vulgare L.; linkage disequilibrium; plant breeding; resistance

Published in

Frontiers in Plant Science
2017, volume: 8, article number: 1954

Authors' information

Swedish University of Agricultural Sciences, Department of Plant Breeding
Swedish University of Agricultural Sciences, Department of Plant Breeding
Manninen, Outi
Boreal Plant Breeding Ltd
Reitan, Lars
Graminor AS
Christerson, Therese
Lantmännen Lantbruk
Jensen, Jens Due
Nordic Seed A/S
Krusell, Lene
Sejet Plant Breeding
Swedish University of Agricultural Sciences, Department of Plant Breeding
Nordic Seed A/S
Orabi, Jihad
Nordic Seed A/S

Associated SLU-program

SLU Plant Protection Network

UKÄ Subject classification

Genetics and Breeding

Publication Identifiers


URI (permanent link to this page)