Research article - Peer-reviewed, 2017
Distribution and seasonal variation of ljungan virus in bank voles (Myodes glareolus) in FennoscandiaFevola, Cristina; Rossi, Chiara; Rosa, Roberto; Nordstrom, Ake; Ecke, Frauke; Magnusson, Magnus; Miller, Andrea L.; Niemimaa, Jukka; Olsson, Gert E.; Jaaskelainen, Anne J.; Hornfeldt, Birger; Henttonen, Heikki; Hauffe, Heidi C.
AbstractLjungan virus (LV) is a picornavirus originally isolated from Swedish bank voles (Myodes glareolus) in 1998. The association of LV with human disease has been debated ever since, but fundamental data on the ecology of the virus are still lacking. Here we present results of the first intensive study on the prevalence of LV in bank voles trapped in Fennoscandia (Sweden and Finland) from 2009-12 as determined by PCR. Using an LV-specific real-time reverse transcriptase PCR, LV was detected in the liver of 73 out of 452 (16.2%) individuals and in 13 out of 17 sampling sites across Sweden and Finland (mean per site prevalence 16%, SE 3%, range 0-50%). We found more infected animals in autumn compared to spring, and lighter and heavier individuals had a higher prevalence than those with intermediate body masses. The result that LV prevalence is also lower in heavier (i.e., older) animals suggests for the first time that LV infection is not persistent in rodents.
KeywordsFinland; Parechovirus B; picornavirus; prevalence; rodent-borne virus; real-time reverse transcriptase PCR; Sweden
Published inJournal of Wildlife Diseases
2017, volume: 53, number: 3, pages: 552-560
Publisher: WILDLIFE DISEASE ASSOC, INC
University of Helsinki
Swedish University of Agricultural Sciences, Department of Aquatic Sciences and Assessment
Swedish University of Agricultural Sciences, Department of Biomedical Science and Veterinary Public Health
Hauffe, Heidi C.
Edmund Mach Foundation
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