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Review article - Peer-reviewed, 2018

Pyometra in Small Animals

Hagman, R


Pyometra is a common disease in dogs and cats. Hormones and opportunistic bacteria are fundamental in the development, with progesterone playing a key role. The disease should be suspected in intact bitches and queens presenting with illness, and particularly if within 4 months after estrus. Early diagnosis and treatment are vital to increase chances of survival as endotoxemia and sepsis often are induced. Typical clinical signs include vaginal discharge, depression, anorexia, polyuria and polydipsia, fever and gastrointestinal disturbances. Surgical ovariohysterectomy is the safest and most effective treatment. For breeding animals with less severe illness, purely medical treatments alternatives are possible.


Endometritis; Cystic endometrial hyperplasia; Escherichia coli; Endotoxemia; Aglepristone; Prostaglandin; Cabergoline; Bromocriptine

Published in

Veterinary Clinics of North America: Small Animal Practice
2018, volume: 48, number: 4, pages: 639-661

Authors' information

Swedish University of Agricultural Sciences, Department of Clinical Sciences

UKÄ Subject classification

Clinical Science

Publication Identifiers


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