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Research article2018Peer reviewedOpen access

Secondary Metabolites from the Root Rot Biocontrol Fungus Phlebiopsis gigantea

Kalvo, David; Menkis, Audrius; Broberg, Anders

Abstract

Three cyclopentanoids (phlebiopsin A C), one glycosylated p-terphenyl (methyl-terfestatin A), and o-orsellinaldehyde were isolated from the biocontrol fungus Phlebiopsis gigantea, and their structures were elucidated by 1D and 2D NMR spectroscopic analysis, as well as by LC-HRMS. The biological activity of the compounds against the root rot fungus Heterobasidion occidentale, as well as against Fusarium oxysporum and Penicillium canescens, was also investigated, but only o-orsellinaldehyde was found to have any antifungal activity in the concentration range tested.

Keywords

Phlebiopsis gigantea; phanerochaetaceae; biocontrol; Heterobasidion spp.; secondary metabolite characterization; cyclopentanoids; p-terphenyls

Published in

Molecules
2018, Volume: 23, number: 6, article number: 1417
Publisher: MDPI